月归档:十一月 2010

Barrett esophagus 巴雷特食管

The normal white appearance of the esophageal epithelium is replaced by irregular red areas that microscopically display columnar metaplasia with scattered goblet cells. This is Barrett esophagus, a complication of long-standing gastroesophageal reflux disease (GERD). Patients with Barrett esophagus usually … 继续阅读

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metastases of malignant melanoma 转移性恶性黑色素瘤

The large black masses seen in the liver represent metastases of malignant melanoma. The microscopic image demonstrates the epithelioid pattern of melanoma with prominent nucleoli and numerous small brown cytoplasmic melanin granules. The urine has a slight brown color, and … 继续阅读

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Chordomas 脊索瘤

[Case contributed by Khaled Al Saad, MD (Department of Pathology and Laboratory Medicine) and Hisham Al Shalaan, MD (Department of Diagnostic Radiology) of King Fahad National Guard Hospital, Riyadh, SAUDI ARABIA] This is a chordoma arising in the region of … 继续阅读

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Squamous cell carcinoma (SCC) 鳞状细胞癌

This large, solitary mass in the lung is a primary squamous cell carcinoma (SCC). Both SCC and small cell anaplastic (‘oat cell’) carcinoma of the lung are strongly correlated with a history of smoking, but the SCC tends to reach … 继续阅读

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Squamous cell carcinoma (SCC) 鳞状细胞癌

This large, solitary mass in the lung is a primary squamous cell carcinoma (SCC). Both SCC and small cell anaplastic (‘oat cell’) carcinoma of the lung are strongly correlated with a history of smoking, but the SCC tends to reach … 继续阅读

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diabetes mellitus 糖尿病

This is an islet of Langerhans in the pancreas. The Congo red stain reveals amyloid deposition, a finding that can be seen with type II diabetes mellitus. This patient will have hyperglycemia and an increased hemoglobin A1C. The protein amylin … 继续阅读

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multiple sclerosis (MS) 多发性硬化症

What laboratory test finding is likely to be present in the cerebrospinal fluid of this young adult woman? There are periventricular plaques of greyish demyelination in white matter characteristic for multiple sclerosis (MS). Women are affected twice as often as … 继续阅读

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scleroderma 硬皮病

The history of difficulty swallowing suggests esophageal dysmotility. The image of the hand demonstrates ischemic necrosis along with a bluish-purple discoloration from Raynaud’s phenomenon. The antinuclear antibody pattern in the Hep-2 cells is nucleolar. These findings suggest scleroderma. The limited … 继续阅读

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myeloma 骨髓瘤

The bone marrow smear shown here demonstrates increased numbers of plasma cells in a case of multiple myeloma, most of which appear similar to normal plasma cells, though there is an abnormal double nucleated plasma cell at the far right. … 继续阅读

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adenoma of the adrenal gland 肾上腺腺瘤

A 47 year old male presented with a 1.5 year history of hypertension that did not respond to therapy with the antihypertensive agents nifedipine and spironolactone. He was found to have hypokalemia. An abdominal CT scan revealed a lesion represented … 继续阅读

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