月归档:四月 2012

Squamous Cell Carcinoma of Cervix 宫颈鳞状细胞癌

Gross specimen photograph showing a polypoid hemorrhagic mass involving the external os. Microscopically, it showed a keratinizing moderately-differentiated squamous cell carcinoma.

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Adenofibroma of Cervix 宫颈腺纤维瘤

The stroma appears to be composed of fibroblasts and exhibits no nuclear pleomorphism or mitotic activity. The tumor is usually non-invasive; however, in rare cases, it may invade endocervical wall or myometrium.

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Melanoma of Cervix 宫颈黑色素瘤

The nuclei are pleomorphic and mitoses are readily seen. In the absence of an in-situ component, distinction from metastatic melanoma may be extremely challenging.

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Decidual Reaction in Cervix 宫颈蜕膜反应

This incidental phenomenon may be confused with early invasive squamous cell carcinoma, especially if it is associated with CIN. Correct diagnosis can be made by attention to bland nuclear features, lack of mitoses, and negativity for cytokeratin.

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Flat Condyloma宫颈扁平湿疣

Higher magnification shows nuclear atypia, including enlargement, variation in size and shape, hyperchromasia, and coarse chromatin. Rare mitotic figures can also be seen.

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Herpes Simplex Virus 宫颈单纯性疱疹病毒

Herpes virus infection of the cervix usually causes a necrotic ulcer which is surrounded by granulation tissue and an inflammatory infiltrate. The infiltrate contains abundant lymphocytes, histiocytes and neutrophils. The image shows characteristic multinucleated cells with ground glass nuclei in … 继续阅读

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Mesonephric Duct Remnants宫颈残留中肾管组织

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Leiomyosarcoma – Vulva外阴平滑肌肉瘤

Smooth muscle tumors of the vulva fulfilling three or more of the following diagnostic criteria can be diagnosed as leiomyosarcoma: > 5 cm in size, > 5 mitoses/10 HPF, infiltrative margins, moderate to severe cytologic atypia.

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Angiomyofibroblastoma 血管肌纤维母细胞瘤

The image shows round to oval, plump spindle cells clustering around delicate vessels. Local excision is usually adequate treatment. Recurrences are uncommon. Rare cases of sarcomatous transformation have been reported. Some angiomyofibroblastomas have foci indistinguishable from aggressive angiomyxoma and the … 继续阅读

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Aggressive Angiomyxoma 侵润性血管粘液瘤

Another example of an aggressive angiomyxoma arising in the vulvar region of a 25 y/o woman. The tumor was hypocellular, poorly circumscribed, composed of bland spindle cells and had matrix of fibrillary collagen.

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