月归档:四月 2012

Rhabdomyoma – Vagina阴道横纹肌瘤

High power view from the previous case shows cross-striations in the well-differentiated rhabdomyoblasts.

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Endometrioid Carcinoma of Vagina子宫内膜腺癌

Higher power view of the previous case shows variably-shaped glands lined by multilayered epithelium. There is superficial resemblance to proliferative phase endometrium, although with greater degree of cytologic atypia.

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Clear Cell Adenocarcinoma of Vagina阴道透明细胞癌

Higher power view from previous case shows many hobnail-shaped cells, some of which have dark atypical nuclei. Differential diagnosis is with microglandular adenosis and Arias-Stella reaction. The overall prognosis of this tumor is relatively good.

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Paget’s Disease of Vulva 外阴派杰氏病

High power view shows large pale tumor cells which are sometimes mistaken for malignant melanoma. The cells contain intracytoplasmic mucin and are positive for mucicarmine, PAS and alcian blue. Immunohistochemical profile includes positivity for MUC1, MUC5AC, CK7, CAM5.2, EMA, CEA, … 继续阅读

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Verrucous Carcinoma 疣状癌

This well-differentiated tumor is a subtype of squamous cell carcinoma and usually presents with an exophytic mass which may become quite large. It infiltrates locally but does not metastasize. The image shows bulbous and finger-like sheets of well-differentiated tumor cells … 继续阅读

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Adenoid Cystic Carcinoma of Bartholin’s Glands前庭大腺腺样囊性癌

Higher power view shows nests and sheets of relatively uniform cells with cribriform appearance. The cribriform areas contain amorphous eosinophilic basement membrane-like material. The tumor behaves aggressively with tendency to metastasize to inguinal lymph nodes. Treatment is by wide local … 继续阅读

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Hyperplasia of Bartholin’s GlandsBartholin前庭大腺异常增生腺体

High power view shows closely-packed glands with benign cytology.

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Bartholin Cyst 前庭大腺囊肿

High power view shows the transitional epithelial lining and mucus glands. Foci of squamous metaplasia are not infrequent. The cyst lining may be partially or completely destroyed by the inflammatory infiltrate.

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Gartner Duct Cyst Gartner管囊肿

Gross specimen photograph of a Gartner Duct Duct. The thick white lining at the top of the image is normal vaginal glycogenated squamous epithelium. The cyst was lined by a mixture of three types of epithelium: vaginal (squamous), transitional, and … 继续阅读

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Melanoma of Vulva 外阴黑色素瘤

About 70% of genital melanomas in female involve labia majora and minora. They occur mainly in older women. The tumor cells in this image show considerable cytologic atypia and melanocytic differentiation with abundant melanin. Important prognostic indicators include thickness (Breslow) … 继续阅读

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