月归档：十一月 2012

Ovarian teratoma showing neuroepithelial tubules and rosettes (immature component) adjacent to a hair follicle (mature component). Although adult-type tissues arising from all three germ layers may be found in dermoid cysts, the ectodermal derivatives are predominant in most cases. They … 继续阅读 →

This 4.0 cm dermoid cyst is filled with greasy material (keratin and sebaceous secretions) and shows tufts of hair. The rounded solid area at the bottom is called Rokitansky’s protruberance. Microscopically, it also showed foci of neural tissue. This case … 继续阅读 →

Close-up of the previous image showing teeth and hair strands. The teeth are sometimes accompanied by rudimentary mandible or maxilla. In addition to these structures, bone, cartilage, fat, and brain tissue may be seen grossly. Image courtesy of Steve O’Connor, … 继续阅读 →

Dermoid cyst is the commonest ovarian tumor comprising almost 50% of all ovarian tumors. Majority of them occur during reproductive years but can also occur in children. Teeth occur in about one-third of cases. A few hair strands are also … 继续阅读 →

Dysgerminoma showing cord-like pattern of tumor cells separated by delicate fibrous septa. About 20% of dysgerminomas are bilateral. The tumor has excellent prognosis with 100% survival for stage I tumors and almost 80-90% for higher stage tumors.

High power view of a dysgerminoma showing anaplastic tumor cells. The cells have discrete cytoplasmic borders, large nuclei with coarse chromatin, prominent nucleoli and brisk mitotic activity. Small lymphocytes are sprinkled throughout the tumor.

The tumor cells in dysgerminomas are may be arranged in sheets (shown here), cords, nests, and trabecular arrangements. Delicate fibrous bands containing lymphocytes traverse the tumor. Note the resemblance to a seminoma.

Dysgerminomas comprise about 1% of all ovarian cancers and are usually seen between the ages of 15 and 30 yrs. The image shows primitive-appearing tumor cells arranged in sheets with areas of dystrophic calcification.