cardiac myxoma 心脏黏液瘤

This high power microscopic appearance of a cardiac myxoma shows minimal cellularity. Only scattered spindle cells with scant pink cytoplasm are present in a loose myxoid stroma. The most common primary cardiac neoplasm is an atrial myxoma. These benign masses are attached to the atrial wall in over 90% of cases, but can also arise on a valve or in a ventricle. They can produce a ‘ball valve’ effect by intermittently occluding the atrioventricular valve orifice to produce clinical findings resembling a transient ischemic attack. Elaboration of interleukin-6 by the tumor may produce fever and malaise. Embolization of a myxoma may also occur. About 10% of cardiac myxoma cases are associated with the Carney syndrome, a familial autosomal dominant condition with a mutated PRKA1 gene. This syndrome is suggested by the presence of multiple cardiac or extracardiac myxomas.

此条目发表在 未分类 分类目录。将固定链接加入收藏夹。

发表评论

电子邮件地址不会被公开。 必填项已被标记为 *

*

您可以使用这些 HTML 标签和属性: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>